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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2021982Generated: October 29, 2026

Methyl propiolate → HCID 121599062, compound

https://huagongshe.com/reaction/2021982

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl propiolateHCID 13536—
Reactant5-BromopyrimidineHCID 78344—
ReagentSodium BicarbonateHCID 516892—
ReagentCopper(I) iodideHCID 6432705—
CatalystDichloro-(4,5-bis(diphenylphosphino)-9,9-dimethylxanthene)palladium(II)HCID 60153068—
SolventAcetonitrileHCID 6342—
ProductHCID 121599062HCID 121599062—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature90 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-84a33ce4f69848958845904295fd77a2
Source note39k HTE dataset from Pfizer