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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2022154Generated: October 30, 2026

tert-Butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate → HCID 178494105, compound

https://huagongshe.com/reaction/2022154

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylateHCID 11435337—
Reactant3-Bromo-2-methoxypyridineHCID 12533390—
ReagentN-Methyl dicyclohexylamineHCID 24210—
ReagentLithium ChlorideHCID 433294—
CatalystDichloro-(4,5-bis(diphenylphosphino)-9,9-dimethylxanthene)palladium(II)HCID 60153068—
SolventDimethylformamideHCID 6228—
ProductHCID 178494105HCID 178494105—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature70 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-2d731f9bc0f34fa3aa51a03ef8ab45e1
Source note39k HTE dataset from Pfizer