1-(2-Bromoethyl)-3-(trifluoromethoxy)benzene → 8-(2,5-Dimethoxy-phenylsulfanyl)-9-[2-(3-trifluoromethoxy-phenyl)-ethyl]-9H-purin-6-ylamine
Reaction equation
[Br:22][CH2:23][CH2:24][c:25]1[cH:26][c:27]([O:31][C:32]([F:33])([F:34])[F:35])[cH:28][cH:29][cH:30]1.[CH3:1][O:2][c:3]1[c:4]([S:11][c:12]2[nH:13][c:14]3[n:15][cH:16][n:17][c:18]([NH2:21])[c:19]3[n:20]2)[cH:5][c:6]([O:9][CH3:10])[cH:7][cH:8]1>>[CH3:1][O:2][c:3]1[c:4]([S:11][c:12]2[n:13]([CH2:23][CH2:24][c:25]3[cH:26][c:27]([O:31][C:32]([F:33])([F:34])[F:35])[cH:28][cH:29][cH:30]3)[c:14]3[n:15][cH:16][n:17][c:18]([NH2:21])[c:19]3[n:20]2)[cH:5][c:6]([O:9][CH3:10])[cH:7][cH:8]1Participants
3
Sources & evidence
- ORD record
- ord-5e7a3714cc0a4a4e99c6900534326fe2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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