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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2022690Generated: October 31, 2026

5-Bromopyrimidine → 1,2-Bis(1,1-dimethylethyl) 1-(5-pyrimidinyl)-1,2-hydrazinedicarboxylate

https://huagongshe.com/reaction/2022690

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-BromopyrimidineHCID 78344—
ReactantDi-tert-butyl bicarbamateHCID 85431—
ReagentHCID 23675099HCID 23675099—
CatalystHCID 178420029HCID 178420029—
Solvent1,4-DioxaneHCID 31275—
Product1,2-Bis(1,1-dimethylethyl) 1-(5-pyrimidinyl)-1,2-hydrazinedicarboxylateHCID 72207624—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature110 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-3aaf1f7ab2134fb5b929169e5b34eb5a
Source note39k HTE dataset from Pfizer