8-Amino-1-isopropyl-5,5-dimethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-one → 3-[[5-chloro-2-[(5,5-dimethyl-2-oxo-1-propan-2-yl-3,4-dihydro-1-benzazepin-8-yl)amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide

HRID 202338Notes

Reaction equation

HRID 202338 reaction equation
[Cl:19][c:20]1[n:21][cH:22][c:23]([Cl:37])[c:24]([NH:26][CH:27]2[CH:28]([C:34](=[O:35])[NH2:36])[CH:29]3[CH:30]=[CH:31][CH:32]2[CH2:33]3)[n:25]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:18]1)[N:7]([CH:15]([CH3:16])[CH3:17])[C:8](=[O:14])[CH2:9][CH2:10][C:11]2([CH3:12])[CH3:13]>>[NH:1]([c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:18]1)[N:7]([CH:15]([CH3:16])[CH3:17])[C:8](=[O:14])[CH2:9][CH2:10][C:11]2([CH3:12])[CH3:13])[c:20]1[n:21][cH:22][c:23]([Cl:37])[c:24]([NH:26][CH:27]2[CH:28]([C:34](=[O:35])[NH2:36])[CH:29]3[CH:30]=[CH:31][CH:32]2[CH2:33]3)[n:25]1

Participants

3

Reactant 2

HCID 672644338-Amino-1-isopropyl-5,5-dimethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-oneHCID 764469493-(2,5-Dichloro-pyrimidin-4-ylamino)-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid amide

Product 1

HCID 1784565313-[[5-chloro-2-[(5,5-dimethyl-2-oxo-1-propan-2-yl-3,4-dihydro-1-benzazepin-8-yl)amino]pyrimidin-4-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide

Sources & evidence

ORD record
ord-3c4026eddbca459d89a6a830a4db6b3a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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