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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2023686Generated: October 30, 2026

Ethylene → 7-bromo-8-chloro-3,4-dihydroisoquinolin-1(2H)-one

https://huagongshe.com/reaction/2023686

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyleneHCID 6325—
ReactantHCID 178476724HCID 178476724—
ReagentSodium BicarbonateHCID 516892—
Catalystdichloro(pentamethylcyclopentadienyl)rhodium (III) dimerHCID 74890113—
SolventMethanolHCID 887—
Product7-bromo-8-chloro-3,4-dihydroisoquinolin-1(2H)-oneHCID 118572053—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-c800008e03f44aeb8faea81106bf01f9
Source note39k HTE dataset from Pfizer