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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2023745Generated: October 30, 2026

Ethylene → 8-chloro-5-methyl-3,4-dihydroisoquinolin-1(2H)-one

https://huagongshe.com/reaction/2023745

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyleneHCID 6325—
ReactantHCID 178476725HCID 178476725—
ReagentMonobasic potassium phosphateHCID 516951—
Catalystdichloro(pentamethylcyclopentadienyl)rhodium (III) dimerHCID 74890113—
Solvent2-MethyltetrahydrofuranHCID 7301—
Product8-chloro-5-methyl-3,4-dihydroisoquinolin-1(2H)-oneHCID 118572062—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-6f9ba238bb084449aba178dc9aa2b7f6
Source note39k HTE dataset from Pfizer