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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2023855Generated: November 1, 2026

Ethylene → 5,8-dichloro-3,4-dihydroisoquinolin-1(2H)-one

https://huagongshe.com/reaction/2023855

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyleneHCID 6325—
Reactant2,5-dichloro-N-methoxybenzamideHCID 25537374—
ReagentSilver carbonateHCID 92796—
Catalystdichloro(pentamethylcyclopentadienyl)rhodium (III) dimerHCID 74890113—
SolventMethanolHCID 887—
SolventAcetonitrileHCID 6342—
Product5,8-dichloro-3,4-dihydroisoquinolin-1(2H)-oneHCID 86723726—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-f63bb14fcb184d0cb45244ed4d901e16
Source note39k HTE dataset from Pfizer