2-Bromo-N-(5-chloro-2-pyridinyl)acetamide → 1-[(5-Chloro-pyridin-2-ylcarbamoyl)-methyl]-2-[2-fluoro-4-(pyrrolidine-1-carbonyl)-phenylcarbamoyl]-1H-benzoimidazole-4-carboxylic acid methyl ester
Reaction equation
[Br:31][CH2:32][C:33](=[O:34])[NH:35][c:36]1[n:37][cH:38][c:39]([Cl:42])[cH:40][cH:41]1.[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][cH:7][cH:8][c:9]2[nH:10][c:11]([C:14]([NH:15][c:16]3[c:17]([F:29])[cH:18][c:19]([C:22](=[O:23])[N:24]4[CH2:25][CH2:26][CH2:27][CH2:28]4)[cH:20][cH:21]3)=[O:30])[n:12][c:13]12>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][cH:7][cH:8][c:9]2[n:10]([CH2:32][C:33](=[O:34])[NH:35][c:36]3[n:37][cH:38][c:39]([Cl:42])[cH:40][cH:41]3)[c:11]([C:14]([NH:15][c:16]3[c:17]([F:29])[cH:18][c:19]([C:22](=[O:23])[N:24]4[CH2:25][CH2:26][CH2:27][CH2:28]4)[cH:20][cH:21]3)=[O:30])[n:12][c:13]12Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-7c21a4a6ede74922be3704b1f95b4a4b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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