Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2024253Generated: October 31, 2026

Acetylene → 4-Chloro-1,7-naphthyridin-8(7H)-one

https://huagongshe.com/reaction/2024253

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetyleneHCID 6326—
ReactantHCID 178447623HCID 178447623—
ReagentSodium CarbonateHCID 10340—
Catalystdichloro(pentamethylcyclopentadienyl)rhodium (III) dimerHCID 74890113—
SolventTolueneHCID 1140—
Product4-Chloro-1,7-naphthyridin-8(7H)-oneHCID 133625243—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature60 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-7d3c09868ad14c8db877dbad435ba61a
Source note39k HTE dataset from Pfizer