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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2026378Generated: November 1, 2026

Tetrabutylammonium Cyanide → 4-Bromo-5-fluoro-2-methylbenzaldehyde

https://huagongshe.com/reaction/2026378

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrabutylammonium CyanideHCID 165872—
Reactant4-Bromo-5-fluoro-2-methylbenzaldehydeHCID 12187217—
Catalystpalladium(II) acetateHCID 167845—
Catalyst(4-(N,N-Dimethylamino)phenyl)di-tert-butyl phosphineHCID 11714598—
SolventDimethylacetamideHCID 31374—
Product4-Bromo-5-fluoro-2-methylbenzaldehydeHCID 12187217—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature100 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-dec4bfbd4f3a4c85b8745acd548f4070
Source note39k HTE dataset from Pfizer