2-Chlorobenzoyl chloride → 2-Chloro-N-(3-{3-[2-(2,3-dihydro-benzo[1,4]dioxin-6-ylamino)-pyrimidin-4-yl]-pyrazolo[1,5-a]pyridin-2-yl}-phenyl)-benzamide

HRID 202657Notes

Reaction equation

HRID 202657 reaction equation
[Cl:34][C:35](=[O:36])[c:37]1[cH:38][cH:39][cH:40][cH:41][c:42]1[Cl:43].[NH2:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][n:10]3[c:11]([cH:12][cH:13][cH:14][cH:15]3)[c:16]2-[c:17]2[n:18][c:19]([NH:23][c:24]3[cH:25][c:26]4[c:27]([cH:32][cH:33]3)[O:28][CH2:29][CH2:30][O:31]4)[n:20][cH:21][cH:22]2)[cH:5][cH:6][cH:7]1>>[NH:1]([c:2]1[cH:3][c:4](-[c:8]2[n:9][n:10]3[c:11]([cH:12][cH:13][cH:14][cH:15]3)[c:16]2-[c:17]2[n:18][c:19]([NH:23][c:24]3[cH:25][c:26]4[c:27]([cH:32][cH:33]3)[O:28][CH2:29][CH2:30][O:31]4)[n:20][cH:21][cH:22]2)[cH:5][cH:6][cH:7]1)[C:35](=[O:36])[c:37]1[cH:38][cH:39][cH:40][cH:41][c:42]1[Cl:43]

Participants

3

Reactant 2

HCID 691102-Chlorobenzoyl chlorideHCID 595138174-[2-(3-Aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-pyrimidinamine

Product 1

HCID 595138832-Chloro-N-(3-{3-[2-(2,3-dihydro-benzo[1,4]dioxin-6-ylamino)-pyrimidin-4-yl]-pyrazolo[1,5-a]pyridin-2-yl}-phenyl)-benzamide

Sources & evidence

ORD record
ord-7c03e9f487bc45ae9a5037ef4476c323
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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