Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2027531Generated: November 4, 2026

Phenylboronic acid pinacol ester → 1-[(4-Methylphenyl)sulfonyl]-4-phenylpiperidine

https://huagongshe.com/reaction/2027531

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenylboronic acid pinacol esterHCID 570673—
Reactant4,5,6,7-Tetrachloro-1,3-dioxoisoindolin-2-yl 1-tosylpiperidine-4-carboxylateHCID 168267479—
ReagentPotassium t-amylateHCID 23683543—
CatalystFerric acetylacetonateHCID 5483663—
Catalystcyclopentane;dicyclohexyl-[2-[(1R)-1-diphenylphosphanylethyl]cyclopentyl]phosphane;ironHCID 134128718—
SolventTetrahydrofuranHCID 8028—
Product1-[(4-Methylphenyl)sulfonyl]-4-phenylpiperidineHCID 4168466—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature60 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-21e1e976888740339984d4d40abb3735
Source note39k HTE dataset from Pfizer