tert-Butyl 2-bromopropanoate → tert-butyl 2-[4-cyano-N-(cyclopropylmethyl)-3-(trifluoromethyl)anilino]propanoate

HRID 202802Notes

Reaction equation

HRID 202802 reaction equation
[Br:18][CH:19]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH3:27].[CH:1]1([CH2:4][NH:5][c:6]2[cH:7][c:8]([C:14]([F:15])([F:16])[F:17])[c:9]([C:10]#[N:11])[cH:12][cH:13]2)[CH2:2][CH2:3]1>>[CH:1]1([CH2:4][N:5]([c:6]2[cH:7][c:8]([C:14]([F:15])([F:16])[F:17])[c:9]([C:10]#[N:11])[cH:12][cH:13]2)[CH:19]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH3:27])[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 545327tert-Butyl 2-bromopropanoateHCID 114818514-[(Cyclopropylmethyl) amino]-2-(trifluoromethyl)benzonitrile

Product 1

HCID 57633736tert-butyl 2-[4-cyano-N-(cyclopropylmethyl)-3-(trifluoromethyl)anilino]propanoate

Sources & evidence

ORD record
ord-38bc65470b5443c4acbcea35eb6147cc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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