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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2028131Generated: October 30, 2026

N-bromobutanimide → 3-Bromo-2-(bromomethyl)-6-chloropyridine

https://huagongshe.com/reaction/2028131

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-bromobutanimideHCID 67184—
Reactant3-Bromo-6-chloro-2-methylpyridineHCID 14866674—
ReagentSulfuric AcidHCID 1118—
CatalystAzobisisobutyronitrileHCID 6547—
SolventTetrahydrofuranHCID 8028—
Product3-Bromo-2-(bromomethyl)-6-chloropyridineHCID 23249915—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature60 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-de5c8510e4454b509bd4da70a2212d1f
Source note39k HTE dataset from Pfizer