Potassium Cation → 4'-{[3-(2,4-dimethoxybenzyl)-6-ethyl-2,4-dioxo-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl]methyl}-3'-fluorobiphenyl-2-carbonitrile

HRID 202873Notes

Reaction equation

HRID 202873 reaction equation
[Br:25][CH2:26][c:27]1[c:28]([F:41])[cH:29][c:30](-[c:33]2[c:34]([C:39]#[N:40])[cH:35][cH:36][cH:37][cH:38]2)[cH:31][cH:32]1.[C:42](=[O:43])([O-:44])[O-:45].[CH3:1][O:2][c:3]1[c:4]([CH2:5][n:6]2[c:7](=[O:18])[nH:8][c:9]3[c:10]([c:11]2=[O:12])[cH:13][c:14]([CH2:16][CH3:17])[s:15]3)[cH:19][cH:20][c:21]([O:23][CH3:24])[cH:22]1.[CH3:48][C:49]#[N:50].[K+:46].[K+:47]>>[CH3:1][O:2][c:3]1[c:4]([CH2:5][n:6]2[c:7](=[O:18])[n:8]([CH2:26][c:27]3[c:28]([F:41])[cH:29][c:30](-[c:33]4[c:34]([C:39]#[N:40])[cH:35][cH:36][cH:37][cH:38]4)[cH:31][cH:32]3)[c:9]3[c:10]([c:11]2=[O:12])[cH:13][c:14]([CH2:16][CH3:17])[s:15]3)[cH:19][cH:20][c:21]([O:23][CH3:24])[cH:22]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 19660Carbonate IonHCID 574600744'-(Bromomethyl)-3'-fluorobiphenyl-2-carbonitrileHCID 593517753-(2,4-dimethoxybenzyl)-6-ethylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione

Product 1

HCID 593514574'-{[3-(2,4-dimethoxybenzyl)-6-ethyl-2,4-dioxo-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl]methyl}-3'-fluorobiphenyl-2-carbonitrile

Sources & evidence

ORD record
ord-a2d765d5a68d471a9672b3abaa513389
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…