HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Fluoride → tert-butyl (3R)-3-[(4-bromo-3-fluorobenzoyl)(3-chloropyridin-2-yl)amino]piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Fluoride | HCID 522689 | — |
| Reactant | HCID 178451960 | HCID 178451960 | — |
| Catalyst | Bis(tricyclohexylphosphine)nickel(II) Dichloride | HCID 11039739 | — |
| Solvent | 2-Methyltetrahydrofuran | HCID 7301 | — |
| Product | tert-butyl (3R)-3-[(4-bromo-3-fluorobenzoyl)(3-chloropyridin-2-yl)amino]piperidine-1-carboxylate | HCID 121276864 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Reaction Conditions
| Temperature | 120 °C |
|---|
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|---|
| Source dataset | 39k HTE dataset from Pfizer |
| ORD ID | ord-3d319b336a3d411cb15ca7390726e72d |
| Source note | 39k HTE dataset from Pfizer |