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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2028958Generated: October 30, 2026

Potassium Fluoride → tert-butyl (3R)-3-[(4-bromo-3-fluorobenzoyl)(3-chloropyridin-2-yl)amino]piperidine-1-carboxylate

https://huagongshe.com/reaction/2028958

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium FluorideHCID 522689—
ReactantHCID 178451960HCID 178451960—
CatalystHCID 178482799HCID 178482799—
Solvent2-MethyltetrahydrofuranHCID 7301—
Producttert-butyl (3R)-3-[(4-bromo-3-fluorobenzoyl)(3-chloropyridin-2-yl)amino]piperidine-1-carboxylateHCID 121276864—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-242b356b5e9344329e2c5f5f6466ac2d
Source note39k HTE dataset from Pfizer