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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2029106Generated: November 2, 2026

Benzylamine → (3S,4R)-4-amino-1-methylsulfonylpiperidin-3-ol

https://huagongshe.com/reaction/2029106

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzylamineHCID 7504—
Reactant(3aS)-1-methyl-3,3-diphenyl-hexahydropyrrolo(1,2-c)(1,3,2)oxazaboroleHCID 2734713—
ReactantHCID 178504951HCID 178504951—
ReagentTitanium isopropoxideHCID 11026—
Product(3S,4R)-4-amino-1-methylsulfonylpiperidin-3-olHCID 178017013—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-fc1049ce44274b7787d20207f08b85e8
Source note39k HTE dataset from Pfizer