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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2029307Generated: October 30, 2026

Cesium fluoride → tert-butyl (3R)-3-[(4-bromo-3-fluorobenzoyl)(3-chloropyridin-2-yl)amino]piperidine-1-carboxylate

https://huagongshe.com/reaction/2029307

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCesium fluorideHCID 25953—
ReactantCaswell No. 736HCID 62656—
ReactantHCID 178451960HCID 178451960—
CatalystHCID 178439012HCID 178439012—
Solvent2-MethyltetrahydrofuranHCID 7301—
Producttert-butyl (3R)-3-[(4-bromo-3-fluorobenzoyl)(3-chloropyridin-2-yl)amino]piperidine-1-carboxylateHCID 121276864—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-85327608aab94487ace0bf5452843ec8
Source note39k HTE dataset from Pfizer