Diethyl(4-chlorobutyl)phosphonate → HCID 22446316, compound

HRID 2030Notes

Reaction equation

HRID 2030 reaction equation
[CH2:1]([N:8]1[C:16]2[C:15](=[O:17])[NH:14][C:13](=[O:18])[N:12]([CH2:19][CH3:20])[C:11]=2[N:10]=[CH:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[CH2:22][CH2:23][CH2:24][CH2:25][P:26]([O:31][CH2:32][CH3:33])(=[O:30])[O:27][CH2:28][CH3:29]>>[CH2:1]([N:8]1[C:16]2[C:15](=[O:17])[N:14]([CH2:22][CH2:23][CH2:24][CH2:25][P:26](=[O:30])([O:31][CH2:32][CH3:33])[O:27][CH2:28][CH3:29])[C:13](=[O:18])[N:12]([CH2:19][CH3:20])[C:11]=2[N:10]=[CH:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 19689195Diethyl(4-chlorobutyl)phosphonateHCID 220073037-Benzyl-3-ethyl-3,7-dihydro-1H-purine-2,6-dione

Product 1

HCID 22446316HCID 22446316, compound

Procedure

The title substance was prepared from 0.04 mol of 7-benzyl-3-ethyl-xanthine and 0.048 mol of diethyl 4-chlorobutanephosphonate analogously to Example 23.

Sources & evidence

ORD record
ord-f4e76ea00e564ed586febf57d57779fb
Source dataset
uspto-grants-1998_03
Patent number
US05728686

Reaction notes

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