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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2030976Generated: October 31, 2026

3,5-Dibromo-4-methylpyridine → 5-Bromo-4-methylpyridine-3-carbonitrile

https://huagongshe.com/reaction/2030976

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Dibromo-4-methylpyridineHCID 819338—
ReactantHCID 178418546HCID 178418546—
CatalystBis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II)HCID 11714597—
SolventDimethylacetamideHCID 31374—
Product5-Bromo-4-methylpyridine-3-carbonitrileHCID 7060681—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-5596e3ac88694782a077f14e95688a41
Source note39k HTE dataset from Pfizer