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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2031264Generated: November 1, 2026

Ammonium Hydroxide → (3R,4R)-4-Amino-1-(methylsulfonyl)piperidin-3-ol

https://huagongshe.com/reaction/2031264

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmonium HydroxideHCID 14923—
ReactantHCID 178504941HCID 178504941—
ReagentSilver(I) trifluoromethanesulfonateHCID 76223—
Solvent2-MethyltetrahydrofuranHCID 7301—
Product(3R,4R)-4-Amino-1-(methylsulfonyl)piperidin-3-olHCID 58777604—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-261dc67a38674f00bb5e4b1489c3e840
Source note39k HTE dataset from Pfizer