Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2031354Generated: November 4, 2026

Ammonium Hydroxide → (3R,4R)-4-Amino-1-(methylsulfonyl)piperidin-3-ol

https://huagongshe.com/reaction/2031354

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmonium HydroxideHCID 14923—
ReactantHCID 178504941HCID 178504941—
ReagentTrimethylsilyl triflateHCID 65367—
Solvent1,2-DichloroethaneHCID 11—
Product(3R,4R)-4-Amino-1-(methylsulfonyl)piperidin-3-olHCID 58777604—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-412c5fb30e3f4b4d94d3997aa39b8b7b
Source note39k HTE dataset from Pfizer