HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2031469Generated: November 1, 2026
1-[(Tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid → tert-Butyl 2-(2-methylpyridin-4-yl)pyrrolidine-1-carboxylate
https://huagongshe.com/reaction/2031469
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-[(Tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid | HCID 268472 | — |
| Reactant | 4-Bromo-2-methylpyridine | HCID 2762835 | — |
| Reagent | Cesium carbonate | HCID 10796 | — |
| Catalyst | 2,2'-Biquinoline | HCID 8412 | — |
| Catalyst | Bis(1,5-cyclooctadiene) nickel | HCID 3032389 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | tert-Butyl 2-(2-methylpyridin-4-yl)pyrrolidine-1-carboxylate | HCID 102543294 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|
| Source dataset | 39k HTE dataset from Pfizer |
|---|
| ORD ID | ord-427ca0ed3d1641b7a4df92289e0f4542 |
|---|
| Source note | 39k HTE dataset from Pfizer |
|---|
