HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2031472Generated: November 1, 2026
4-Bromo-2-methylpyridine → tert-Butyl 2-(2-methylpyridin-4-yl)pyrrolidine-1-carboxylate
https://huagongshe.com/reaction/2031472
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Bromo-2-methylpyridine | HCID 2762835 | — |
| Reactant | Potassium (1-((tert-butoxy)carbonyl)pyrrolidin-2-yl)trifluoroboranuide | HCID 74787601 | — |
| Reagent | Cesium carbonate | HCID 10796 | — |
| Catalyst | Bis(1,5-cyclooctadiene) nickel | HCID 3032389 | — |
| Catalyst | 4,4'-Di-tert-butyl-2,2'-bipyridyl | HCID 4249187 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | tert-Butyl 2-(2-methylpyridin-4-yl)pyrrolidine-1-carboxylate | HCID 102543294 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|
| Source dataset | 39k HTE dataset from Pfizer |
|---|
| ORD ID | ord-e1abc254e3fa49609f8becf91362ee8a |
|---|
| Source note | 39k HTE dataset from Pfizer |
|---|
