HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2031480Generated: November 2, 2026
1-[(Tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid → tert-Butyl 2-(2-methylpyridin-4-yl)pyrrolidine-1-carboxylate
https://huagongshe.com/reaction/2031480
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-[(Tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid | HCID 268472 | — |
| Reactant | 4-Bromo-2-methylpyridine | HCID 2762835 | — |
| Reagent | 2,6-Lutidine | HCID 7937 | — |
| Catalyst | 6-Methyl-2,2'-bipyridine | HCID 639521 | — |
| Catalyst | Bis(1,5-cyclooctadiene) nickel | HCID 3032389 | — |
| Solvent | Acetone | HCID 180 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | tert-Butyl 2-(2-methylpyridin-4-yl)pyrrolidine-1-carboxylate | HCID 102543294 | — |
| Internal standard | 9-Phenylanthracene | HCID 11766 | — |
Provenance & Evidence
| DOI | 10.1038/s41557 |
|---|
| Source dataset | 39k HTE dataset from Pfizer |
|---|
| ORD ID | ord-299f1ba61cb84c99ba89ff025584c791 |
|---|
| Source note | 39k HTE dataset from Pfizer |
|---|
