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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2031492Generated: November 1, 2026

1-[(Tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid → HCID 178480191, compound

https://huagongshe.com/reaction/2031492

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[(Tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acidHCID 268472—
Reactant3-Bromo-1-methyl-1H-pyrazoleHCID 14948637—
Reagent2,6-LutidineHCID 7937—
CatalystBis(1,5-cyclooctadiene) nickelHCID 3032389—
Catalyst4,4'-Di-tert-butyl-2,2'-bipyridylHCID 4249187—
SolventAcetoneHCID 180—
SolventMethanolHCID 887—
ProductHCID 178480191HCID 178480191—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-e0134d548f6a4dc9a806720f49b8f077
Source note39k HTE dataset from Pfizer