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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2032050Generated: October 30, 2026

Ammonia → (3R,4R)-4-Amino-1-(methylsulfonyl)piperidin-3-ol

https://huagongshe.com/reaction/2032050

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantChlorobis((1R,2S,3R,5R)-2,6,6-trimethylbicyclo[3.1.1]heptan-3-yl)boraneHCID 11131038—
ReactantHCID 178504951HCID 178504951—
Product(3R,4R)-4-Amino-1-(methylsulfonyl)piperidin-3-olHCID 58777604—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature25 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-2978ff22a71240c7b00773653a8d0805
Source note39k HTE dataset from Pfizer