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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2033873Generated: October 31, 2026

4-Chloro-alpha,alpha,alpha-trifluoro-3-nitrotoluene → HCID 178426507, compound

https://huagongshe.com/reaction/2033873

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-alpha,alpha,alpha-trifluoro-3-nitrotolueneHCID 8462—
Reactant2-Amino-4,6-dimethyl pyrimidineHCID 13021—
ReagentLithium HexamethyldisilazideHCID 2733832—
SolventTetrahydrofuranHCID 8028—
ProductHCID 178426507HCID 178426507—
Internal standard9-PhenylanthraceneHCID 11766—

Reaction Conditions

Temperature50 °C

Provenance & Evidence

DOI10.1038/s41557
Source dataset39k HTE dataset from Pfizer
ORD IDord-09d2293b9a034c649923b7577f7034dc
Source note39k HTE dataset from Pfizer