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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 203397Generated: October 27, 2026

Acetonitrile → 2,2,2-Trifluoro-1-(9-(3-fluoro-5-(2-hydroxyethyl)benzyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)ethanone

https://huagongshe.com/reaction/203397

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
ReactantTrifluoroacetic acidHCID 6422—
ReactantTriethylamineHCID 8471—
Reactant2,2,2-Trifluoro-1-(1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)ethanoneHCID 57989026—
Reactant2-(3-(Bromomethyl)-5-fluorophenyl)ethanolHCID 57989345—
Product2,2,2-Trifluoro-1-(9-(3-fluoro-5-(2-hydroxyethyl)benzyl)-1-oxa-4,9-diazaspiro[5.5]undecan-4-yl)ethanoneHCID 57989380—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-c51955c4140447839b62ff92a6e6316c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)