4-Amino-1-Boc-piperidine → 4-[4-Amino-5-(2-methoxy-benzoyl)-pyrimidin-2-ylamino]-piperidine-1-carboxylic acid tert-butyl ester

HRID 203455Notes

Reaction equation

HRID 203455 reaction equation
[NH2:1][c:2]1[n:3][c:4]([S:18]([CH2:19][CH3:20])(=[O:21])=[O:22])[n:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([O:16][CH3:17])[cH:12][cH:13][cH:14][cH:15]1.[NH2:23][CH:24]1[CH2:25][CH2:26][N:27]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:28][CH2:29]1>>[NH2:1][c:2]1[n:3][c:4]([NH:23][CH:24]2[CH2:25][CH2:26][N:27]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:28][CH2:29]2)[n:5][cH:6][c:7]1[C:8](=[O:9])[c:10]1[c:11]([O:16][CH3:17])[cH:12][cH:13][cH:14][cH:15]1

Participants

3

Reactant 2

HCID 12682914-Amino-1-Boc-piperidineHCID 11961965(4-Amino-2-ethanesulfonylpyrimidin-5-yl)-(2-methoxyphenyl)-methanone

Product 1

HCID 119752004-[4-Amino-5-(2-methoxy-benzoyl)-pyrimidin-2-ylamino]-piperidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-69fda64104cb47d8b97214f78eba4a8e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…