HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2035406Generated: October 30, 2026
Potassium Carbonate → 6-(benzyloxy)-3,4-dihydronaphthalen-1(2H)-one
https://huagongshe.com/reaction/2035406
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 6-Hydroxy-3,4-dihydro-1(2H)-naphthalenone | HCID 4679494 | — |
| Solvent | Acetone | HCID 180 | — |
| Solvent | Benzyl Bromide | HCID 7498 | — |
| Product | 6-(benzyloxy)-3,4-dihydronaphthalen-1(2H)-one | HCID 10682241 | 182.5% |
Reaction Steps
To a solution of 6-hydroxy-3,4-dihydronaphthalen-1(2H)-one (24.3 g) in acetone (160 mL), benzyl bromide (29.4 mL) and potassium carbonate (31.1 g) were added at room temperature, followed by stirring at 40° C. for 3.5 hours. After filtering off the insoluble matters and concentrating the filtrate, the resultant was washed with a mixed solvent of tert-butyl methyl ether-hexane (1:4), to thereby obtain the title compound (34.5 g) having the following physical properties.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08575134B2 |
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| Source dataset | uspto-grants-2013_11 |
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| ORD ID | ord-61e6a39f0dd8499ab70a4ad40dbe6796 |
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| Source note | uspto-grants-2013_11 |
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