Ethanolamine → HCID 131730944, compound

Participants

Reaction Steps

20 mg of 4-(benzylamino)-6-{[4-(4-ethoxycarbonylpiperidino)phenyl]amino}pyridine-3-carboxyamide (Example 175) and 50 mg of ethanolamine were stirred at 150° C. for 2 hours. After cooling, the reaction mixture was purified by silica gel thin layer chromatography (chloroform:methanol=5:1) to obtain 20 mg (89%) of the title compound as a slight yellow crystalline powder.

Provenance & Evidence