2-Pyridinemethanamine → HCID 58450753, compound

HRID 2035536Notes

Reaction equation

HRID 2035536 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]([Cl:13])=[CH:10][C:11]=1Cl)=[O:5])[CH3:2].[NH2:14][CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=1>>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[N:8][C:9]([Cl:13])=[CH:10][C:11]=1[NH:14][CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][N:17]=1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 195092-PyridinemethanamineHCID 600045Ethyl 4,6-dichloropyridine-3-carboxylate

Product 1

HCID 58450753HCID 58450753, compound

Procedure

From 4,6-dichloropyridine-3-carboxylic acid ethyl ester synthesized according to the method described in US2006/0217417 and 2-(aminomethyl)pyridine in a manner similar to Example 339, the title compound was obtained as a colorless crystalline powder (yield 71%).

Sources & evidence

ORD record
ord-4377e18544924b239cfd935882a475c0
Source dataset
uspto-grants-2013_11
Patent number
US08575153B2

Reaction notes

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