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2-Hydrazinyl-4-iodopyridine → N-[(E)-[8-[tert-butyl(dimethyl)silyl]oxyquinolin-2-yl]methylideneamino]-4-iodopyridin-2-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Hydrazinyl-4-iodopyridine | HCID 53402897 | — |
| 反応物 | 8-(Tert-butyldimethylsilyloxy)quinoline-2-carbaldehyde | HCID 58567082 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | N-[(E)-[8-[tert-butyl(dimethyl)silyl]oxyquinolin-2-yl]methylideneamino]-4-iodopyridin-2-amine | HCID 178455024 | — |
反応手順
To 8-(tert-butyldimethylsilyloxy)quinoline-2-carbaldehyde (3.21 g, 11.2 mmol) in DCM (30 mL) was added (Z)-1-(4-iodopyridin-2(1H)-ylidene)hydrazine (3.15 g, 13.4 mmol). The reaction was stirred for 1 hour, affording a yellow precipitate, which was collected by filtration and used without further purification in the next step.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08575145B2 |
| 出典データセット | uspto-grants-2013_11 |
| ORD ID | ord-4ead848e64ad49ceb87385ce2a7e726d |
| 出典メモ | uspto-grants-2013_11 |