Hydrochloric Acid → HCID 46174559, compound

Participants

Reaction Steps

The product from Step B (0.070 g, 0.14 mmol) was dissolved in CHCl3 (1.4 mL). Then HCl (1.4 mL, 5.7 mmol, 4.0M in dioxane) was added and the mixture stirred at ambient temperature for 5.0 hours. The mixture was filtered directly and the solid washed with CH2Cl2 followed by Et2O and dried. The crude solid was purified by preparative TLC (1 mm, 8% MeOH/DCM with 1% NH3). This provided 0.031 g (56%) of the product as a pale orange solid. MS ESI (+) m/z 390.2 (M+1) detected.

Provenance & Evidence