HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl N-(3-hydroxy-2,2-dimethylpropyl)carbamate → Tert-butyl 3-(2-(6-bromo-[1,2,4]triazolo[4,3-a]pyridin-3-yl)quinolin-8-yloxy)-2,2-dimethylpropylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl N-(3-hydroxy-2,2-dimethylpropyl)carbamate | HCID 21263232 | — |
| Reactant | 2-(6-Bromo-[1,2,4]triazolo[4,3-a]pyridin-3-yl)quinolin-8-ol | HCID 136337807 | — |
| Product | Tert-butyl 3-(2-(6-bromo-[1,2,4]triazolo[4,3-a]pyridin-3-yl)quinolin-8-yloxy)-2,2-dimethylpropylcarbamate | HCID 67230058 | — |
Reaction Steps
Prepared as described in Example 9, Step A, using tert-butyl 3-hydroxy-2,2-dimethylpropylcarbamate in place of tert-butyl-4-hydroxypiperidine-1-carboxylate and 2-(6-bromo-[1,2,4]triazolo[4,3-a]pyridin-3-yl)quinolin-8-ol in place of 2-([1,2,4]triazolo[4,3-a]pyridin-3-yl)quinolin-8-ol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575145B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-cdce101733424646b6016ef5f0f4244f |
| Source note | uspto-grants-2013_11 |