HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydrazinyl-4-methylpyridine → N-[(E)-[8-[tert-butyl(dimethyl)silyl]oxyquinolin-2-yl]methylideneamino]-4-methylpyridin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Hydrazinyl-4-methylpyridine | HCID 12266739 | — |
| Reactant | 8-(Tert-butyldimethylsilyloxy)quinoline-2-carbaldehyde | HCID 58567082 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-[(E)-[8-[tert-butyl(dimethyl)silyl]oxyquinolin-2-yl]methylideneamino]-4-methylpyridin-2-amine | HCID 67230767 | 81% |
Reaction Steps
2-Hydrazinyl-4-methylpyridine (0.280 g, 2.27 mmol) and 8-(tert-butyldimethylsilyloxy)quinoline-2-carbaldehyde (0.653 g, 2.27 mmol) were suspended in EtOH (6 mL) and stirred overnight at ambient temperature. The resulting suspension was filtered and the solid was washed with cold EtOH and dried in vacuo to provide the title compound (0.720 g; 81%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575145B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-a644c984bf624698829627216e52a21a |
| Source note | uspto-grants-2013_11 |