HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-5-hydroxypyridine → 6-fluoro-3-(4-{4-[(6-methylpyridin-3-yl)oxy]phenyl}-1H-1,2,3-triazol-1-yl)-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-5-hydroxypyridine | HCID 14275 | — |
| Reactant | 6-fluoro-3-(4-{4-[(2-methylpyridin-3-yl)oxy]phenyl}-1H-1,2,3-triazol-1-yl)-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one | HCID 46841726 | — |
| Product | 6-fluoro-3-(4-{4-[(6-methylpyridin-3-yl)oxy]phenyl}-1H-1,2,3-triazol-1-yl)-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one | HCID 58063600 | — |
Reaction Steps
Prepared as for 6-fluoro-3-(4-{4-[(2-methylpyridin-3-yl)oxy]phenyl}-1H-1,2,3-triazol-1-yl)-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one, using 5-hydroxy-2-methylpyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575150B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-a5e31a4044ca416fae38b5cdd15256e4 |
| Source note | uspto-grants-2013_11 |