HRID2035720

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Cc1ncccc1Oc1ccc(-c2cn(C3CCc4c(F)cccc4N(CC(F)(F)F)C3=O)nn2)cc1

HCID46841726

未命名化合物

HCID178429033

未命名化合物

PRODUCTS

生成物

结构：Cc1cc(Oc2ccc(-c3cn(C4CCc5c(F)cccc5N(CC(F)(F)F)C4=O)nn3)cc2)cc(C)n1

HCID58063620

未命名化合物

PROCEDURE

实验过程

Prepared as for 6-fluoro-3-(4-{4-[(2-methylpyridin-3-yl)oxy]phenyl}-1H-1,2,3-triazol-1-yl)-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one, using 2,6-dimethyl-4-hydroxypyridine.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-15dd4337a1714506ba5a364c9e79e7d1
来源数据集: uspto-grants-2013_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08575150B2
来源说明: uspto-grants-2013_11

反应 SMILES

[F:1][C:2]1[C:7]2[CH2:8][CH2:9][CH:10]([N:19]3[CH:23]=[C:22]([C:24]4[CH:29]=[CH:28][C:27]([O:30]C5C(C)=NC=CC=5)=[CH:26][CH:25]=4)[N:21]=[N:20]3)[C:11](=[O:18])[N:12]([CH2:13][C:14]([F:17])([F:16])[F:15])[C:6]=2[CH:5]=[CH:4][CH:3]=1.[CH3:38][C:39]1[CH:44]=[C:43](O)[CH:42]=[C:41]([CH3:46])[N:40]=1>>[CH3:38][C:39]1[CH:44]=[C:43]([O:30][C:27]2[CH:28]=[CH:29][C:24]([C:22]3[N:21]=[N:20][N:19]([CH:10]4[CH2:9][CH2:8][C:7]5[C:2]([F:1])=[CH:3][CH:4]=[CH:5][C:6]=5[N:12]([CH2:13][C:14]([F:17])([F:16])[F:15])[C:11]4=[O:18])[CH:23]=3)=[CH:25][CH:26]=2)[CH:42]=[C:41]([CH3:46])[N:40]=1