HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 1'-[6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazin-3-yl]-3H-spiro[1-benzofuran-2,4'-piperidine]
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Chloro-6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazine | HCID 10921829 | — |
| Reactant | 3H-Spiro(1-benzofuran-2,4'-piperidine) | HCID 12733230 | — |
| Product | 1'-[6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazin-3-yl]-3H-spiro[1-benzofuran-2,4'-piperidine] | HCID 68558566 | — |
Reaction Steps
The object product (49 mg, 56%) was obtained in the same manner as in Example 1 and using 3-chloro-6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazine (50 mg), 3H-spiro[1-benzofuran-2,4′-piperidine] (50 mg) and potassium carbonate (50 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575167B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-b0ea83b057f94bfdbe6d3972af54032d |
| Source note | uspto-grants-2013_11 |