HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 3-Methyl-8-[6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazin-3-yl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Chloro-6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazine | HCID 10921829 | — |
| Reactant | 3-Methyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one dihydrochloride | HCID 68558328 | — |
| Product | 3-Methyl-8-[6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazin-3-yl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one | HCID 68556152 | — |
Reaction Steps
The object product (85 mg, 33%) was obtained in the same manner as in Example 1 and using 3-chloro-6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazine (130 mg), 3-methyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one dihydrochloride (223 mg) and potassium carbonate (130 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575167B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-91bcad9257c74adea0a243b5aaf564bc |
| Source note | uspto-grants-2013_11 |