HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 1'-[6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazin-3-yl]-3H-spiro[2-benzofuran-1,3'-pyrrolidine]
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 3-Chloro-6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazine | HCID 10921829 | — |
| Reactant | 3H-Spiro[2-benzofuran-1,3'-pyrrolidine] | HCID 22012187 | — |
| Product | 1'-[6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazin-3-yl]-3H-spiro[2-benzofuran-1,3'-pyrrolidine] | HCID 68555055 | — |
Reaction Steps
The object product (82 mg, 41%) was obtained in the same manner as in Example 1 and using 3-chloro-6-(3-methyl-1,2,4-thiadiazol-5-yl)pyridazine (120 mg), 3H-spiro[2-benzofuran-1,3′-pyrrolidine] (100 mg) and potassium carbonate (138 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575167B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-218e33cb71624f81aed271a5b011fb9a |
| Source note | uspto-grants-2013_11 |