HCID 66653929, compound → HCID 66655978, compound

HRID 2036231Notes

Reaction equation

HRID 2036231 reaction equation
C(OC(N1CC2C(=CC=CC=2)C1C1C=C(Cl)C=CC=1OCC(OCC)=O)=O)(C)(C)C.[CH2:31]([O:38][C:39]([N:41]1[CH2:49][C:48]2[C:43](=[CH:44][CH:45]=[CH:46][CH:47]=2)[CH:42]1[C:50]1[CH:55]=[C:54]([Cl:56])[CH:53]=[CH:52][C:51]=1[O:57][CH2:58][C:59]([O:61][CH2:62][CH3:63])=[O:60])=[O:40])[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1>>[CH2:31]([O:38][C:39]([N:41]1[CH2:49][C:48]2[C:43](=[CH:44][CH:45]=[CH:46][CH:47]=2)[C@H:42]1[C:50]1[CH:55]=[C:54]([Cl:56])[CH:53]=[CH:52][C:51]=1[O:57][CH2:58][C:59]([O:61][CH2:62][CH3:63])=[O:60])=[O:40])[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1

Participants

3

Reactant 2

HCID 66653929HCID 66653929, compoundHCID 66654317HCID 66654317, compound

Product 1

HCID 66655978HCID 66655978, compound

Procedure

Following the same procedure, but starting from (±)-1-(5-chloro-2-ethoxycarbonylmethoxy-phenyl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester, (±)-1-(5-chloro-2-ethoxycarbonylmethoxy-phenyl)-1,3-dihydro-isoindole-2-carboxylic acid benzyl ester was prepared.

Workup

  1. customwas prepared

Sources & evidence

ORD record
ord-3cad8d7f79bb4bbcbfe5b8e2012bc0ad
Source dataset
uspto-grants-2013_11
Patent number
US08575158B2

Reaction notes

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