HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acrylonitrile → 1-(4-Bromophenyl)-1H-pyrazol-3-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acrylonitrile | HCID 7855 | — |
| Reactant | 4-Bromophenylhydrazine | HCID 12158 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Sodium ethoxide | HCID 2723922 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(4-Bromophenyl)-1H-pyrazol-3-amine | HCID 23464285 | — |
Reaction Steps
The title compound was prepared by the reaction of 4-bromophenylhydrazine with acrylonitrile in the presence of a suitable base such as sodium ethoxide in refluxing ethanol followed by oxidation with N-bromosuccinimide; 1H NMR (300 MHz, DMSO-d6) δ 3.81 (br s, 2H), 5.84 (s, 1H), 7.41 (d, J=8.7 Hz, 2H), 7.47 (d, J=8.7 Hz, 2H), 7.63 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575178B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-c8da24001b58426680005dc556063e0d |
| Source note | uspto-grants-2013_11 |