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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2036345Generated: October 27, 2026

2-(Oxolan-2-yl)ethan-1-amine → 2-(Butyloxy)-8-(methyloxy)-9-(3-{[2-(tetrahydro-2-furanyl)ethyl]amino}propyl)-9H-purin-6-amine

https://huagongshe.com/reaction/2036345

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Oxolan-2-yl)ethan-1-amineHCID 4854736—
Reactant2-(Butyloxy)-8-(methyloxy)-9-{3-[(tetrahydro-2-furanylmethyl)amino]propyl}-9H-purin-6-amineHCID 67211570—
ReactantHCID 178450357HCID 178450357—
Product2-(Butyloxy)-8-(methyloxy)-9-(3-{[2-(tetrahydro-2-furanyl)ethyl]amino}propyl)-9H-purin-6-amineHCID 67211317—

Reaction Steps

Prepared similarly to Intermediate 15 from 2-(butyloxy)-8-(methyloxy)-1H-purin-6-amine trifluoroacetate and 2-(tetrahydro-2-furanyl)ethanamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08575181B2
Source datasetuspto-grants-2013_11
ORD IDord-c82bbb1d3695485aaf4d0bbdd8d08c67
Source noteuspto-grants-2013_11