HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-3-Aminotetrahydrofuran → 2-{[(1S)-1-Methylbutyl]oxy}-8-(methyloxy)-9-{4-[(3S)-tetrahydro-3-furanylamino]butyl}-9H-purin-6-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-3-Aminotetrahydrofuran | HCID 14243168 | — |
| Reactant | 9-(4-Chlorobutyl)-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-6-amine | HCID 58290933 | — |
| Reactant | 2-{[(1S)-1-Methylbutyl]oxy}-8-(methyloxy)-9-{4-[(3R)-tetrahydro-3-furanylamino]butyl}-9H-purin-6-amine | HCID 58290959 | — |
| Product | 2-{[(1S)-1-Methylbutyl]oxy}-8-(methyloxy)-9-{4-[(3S)-tetrahydro-3-furanylamino]butyl}-9H-purin-6-amine | HCID 58290960 | — |
Reaction Steps
Prepared similarly to Intermediate 40 from 9-(4-chlorobutyl)-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-6-amine and (3S)-tetrahydro-3-furanamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08575181B2 |
| Source dataset | uspto-grants-2013_11 |
| ORD ID | ord-289b3d6762f8422f873dcfa66f9ecf1b |
| Source note | uspto-grants-2013_11 |