Dimethyl Sulfide → HCID 67432215, compound

Participants

Reaction Steps

The mixture of [1-(3-pyridin-2-yl-imidazo[1,2-a]pyrazin-2-yl)-ethyl]-carbamic acid benzyl ester (450 mg, 1.2 mmol) and dimethylsulfide (1.0 mL) in TFA (4.0 mL) was stirred at rt overnight. The mixture was concentrated in vacuo, and the residue was dissolved in EtOAc. The organic layer was washed with satd. sodium bicarbonate solution, dried over sodium sulfate, filtered and concentrated in vacuo to provide 1-(3-pyridin-2-yl-imidazo[1,2-a]pyrazin-2-yl)-ethylamine: LC-MS (ESI) m/z 240.0 [M+H]+.

Provenance & Evidence