Benzenesulfinic acid, sodium salt → HCID 67085715, compound

Participants

Reaction Steps

The product of step A was coupled with sodium benzenesulfinate following the procedure of Example 27, step C. The crude material was purified by flash column chromatography (SiO2, 4:1 to 1:1 hexane/ethyl acetate) to give tert-butyl 2-phenylsulfonyl-5-ethyl-5,6,7,8,9,10-hexahydro-7,10-epiminocyclohepta[b]indole-carboxylate (0.12 g, 36%) as a white solid: 1H NMR (CDCl3, 300 MHz) δ 8.20 (s, 1H), 7.94-7.99 (m, 2H), 7.40-7.53 (m, 4H), 7.31 (d, J=8.7 Hz, 1H), 5.20-5.33 (m, 1H), 4.55-4.81 (m, 1H), 3.95-4.11 (m, 2H), 3.19-3.50 (m, 1H), 2.47 (d, J=16.2 Hz, 1H), 2.15-2.38 (m, 2H), 1.91-2.01 (m, 1H), 1.53-1.62 (m, 1H), 1.34 (s, 9H), 1.25-1.31 (m, 3H).

Provenance & Evidence